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Remdesivir drug development tracking

Last updated at Posted at 2020-04-07

Open data analysis

Open-science-for-unexpected-discovery

Heuristically-confidenced-semantic-drug-repositioning-without-data-for-quick-remedy(In early phase)

Virus-assembly-analysis-and-synthetic-cell-technology

Unobservable-microscopic-dynamics-simulation

Simulation of pandemics

Infection-control

Pre-discussed-pandemics

Time-series-infection-vizualization

Corona-virus-culture & vaccine, antibody assay

First-report-from-australia

Whole-genome-sequencing

GridION-and-necessity-of-sequencing-performance

Transcriptome-analysis(or-prediction)-and-target-protein-determination

Diagnosing corona-virus infection

RT-PCR

Basic-drug-engineering

Drug-engineering

Main-protease-simulation

Main-protease-simulation

Docking-simulation-with-generative-modeling

Drug-finding-to-antagonize-activity-site-with-generative-modeling

Gao W, Coley CW. The Synthesizability of Molecules Proposed by Generative Models [published online ahead of print, 2020 Apr 6]. J Chem Inf Model. 2020;10.1021/acs.jcim.0c00174. doi:10.1021/acs.jcim.0c00174

Drug-candidate-synthesis & drug-repositioning

Drug-repositioning-research-for-covid-19

Remdesivir-synthesis

Preclinical-trial

Spike-protein-injection(vaccination)-to-the-mice-and-survival-analysis

Immune-system-type-identification-with-latent-time

Immunohistochemistry-for-easy-virus-localization-identification

Linking-ct-or-xray-dataset-to-ihc-dataset-with-mice-for-transfer-learning-to-human

Systematic-xray-dataset-handling

Calculation-of-HED-and-lethal-dose

Drug-administration-design

Optimization-of-drug-carrier-to-the-lung

Clinical-trial

Remdesivir-clinical-trial-information-platform

Patient-blood-plasma-injection-or-remdesivir-decision(Effective-pattern-analysis)

PhaseI

PhaseII

PhaseⅢ

PhaseⅢ-clinical-trial-has-already-started

Approval

Pfizer’s-vaccine-approved-in-British

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