添付ファイルに kext あり
$ download and extract
$ cd /path/to/osx-pl2303.kext
$ sudo cp -R osx-pl2303.kext /System/Library/Extensions/
$ next you need to fix permissions and execute bits:
$ cd /System/Library/Extensions
$ sudo chmod -R 755 osx-pl2303.kext
$ sudo chown -R root:wheel osx-pl2303.kext
$ cd /System/Library/Extensions
$ sudo kextload ./osx-pl2303.kext
$ sudo kextcache -system-cache
thanks http://www.xbsd.nl/2011/07/pl2303-serial-usb-on-osx-lion.html
% ls /dev/tty.*
/dev/tty.Bluetooth-Modem /dev/tty.Bluetooth-PDA-Sync /dev/tty.PL2303-000012FD